Table 2.

Summary of genes analyzed using SKAT-O, based on variants in exons and UTRs.

SKAT-O analysis	MAF filter	Genes	SNVs	MAF weighting in SKAT
WES-common	MAF > 0.05	10,228	25,355	No
WES-rare	MAF < 0.01 and missing in gnomAD	17,318	142,006	Yes
WES-ultra-rare	MAF < 0.001	14,898	59,092	Yes