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Protective role of high-density lipoprotein (HDL) in cancer development. ABCA1, ATP-binding cassette transporter; Akt, protein kinase B; Apo-A1, apolipoprotein A-I; HDL, high-density lipoprotein; MMP-9, matrix metallopeptidase-9; mTOR, mammalian target of rapamycin; PI-3K, phosphatidyl inositol 3-kinase; SR-BI, scavenger receptor class B type 1; TCA, trichloroacetic acid.
