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. 2020 Sep 25;25(19):4410. doi: 10.3390/molecules25194410

Figure 3.

Figure 3

The potential mechanisms of virus to attack mitochondrial melatonin synthetic pathway. MOM: mitochondrial outer membrane, MIM: mitochondrial inner membrane, IDO: indolamine 2,3 dioxygenase, LDH, lactate dehydrogenase, PDH: pyruvate dehydrogenase, AADC: aromatic amino acid decarboxylase, AANAT: arylalkylamine N-acetyltransferase, HIOMT: hydroxyindole-O-methyltransferase, also known as N-acetylserotonin O-methyltransferase (ASMT). Black upward arrows: stimulating activities of the virus, ┴: suppressive activities of virus.