The effects of plasma and total blood exosomes on tube formation in HUVECs. (A–F): Representative images showing tube formation in HUVECs treated with PBS (negative control) (A), exosomes from the plasma (B) and total blood (C) of BCPs, 10% FBS (positive control) (D), exosomes from the plasma (E) and total blood (F) of HFs. Scale bar is 50 mkm. (G) Quantitative analysis of the tube formation assay. The values for the total tube length were measured (mean ± SEM, * p < 0.05 vs. negative control, ** p < 0.05 vs. exosomes from plasma of HFs, *** p < 0.05 vs. exosomes from total blood of BCPs).