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. 2020 Oct 22;10:18023. doi: 10.1038/s41598-020-75024-6

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Predictions for the association of plastic with the liver metal concentration of prions, though pre-storm body condition is unknown. The null hypothesis is that there is no difference in liver metal(loid) concentration between prions with and without ingested plastic. Significant differences in the concentration of liver metal(loid)s leads to rejection of the null hypothesis and examination of support for two mechanistic association predictions derived from the literature: transfer of metal(loid)s from plastic or malnutrition due to dietary dilution by plastic in the gut. Essential metals are shown in green, non-essential metals are shown in red, and metals where the biological role is unclear are shown in blue. Prion silhouettes were created using GIMP⁸⁸.