Figure 1.

Schematic depiction of the hybridization-based bioassay. (a) Proof-of-concept direct genoassay for the detection of a model target b-A₂₀; with/without amplification strategy based on multivalent system biotin-streptavidin. (b) Sandwich genoassay for the detection of T_PCA3. Note that more than one capture probe is immobilized onto each MB but, for the sake of clarity, the figure only shows one DNA strand. (c) Quantification step, either with the personal glucose meter or spectrophotometrically.