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. 2020 Sep 24;25(19):4394. doi: 10.3390/molecules25194394

Table 2.

Isoform selectivity profile of hybrid 19 against class-I,-II and -IV HDACs.

HDAC Class
HDAC Isoform
I IIa IIb IV
1 2 3 8 4,5,7,9 6 10 11
IC50 (nM) or % inhibition 222 49 2170 740 <20% at 10 µM 2.1 80 930