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. Author manuscript; available in PMC: 2020 Oct 23.
Published in final edited form as: Free Radic Biol Med. 2019 Dec 20;147:200–211. doi: 10.1016/j.freeradbiomed.2019.12.019

Fig. 4.

Fig. 4.

Time dependent inactivation of SmTGR WT and E330/D334 by compounds 4 and 1. The calculated second order rate constants for the inhibition of SmTGR WT and E330/D334 by 4 are respectively: 2.75 × 10−3 μM−1 min−1 and 8.81 × 10−4 μM−1 min−1; while the second order inhibition rates of SmTGR WT and E330/D334 by 1 are: 0.11 μM−1 min−1 and 0.08 μM−1 min−1.