FIG 2.
Measurement of metabolite levels using single-voxel MR spectroscopy in a low-grade glioma with increased contrast enhancement and malignant transformation. Transverse contrast-enhanced T1WI (left) shows an enhancing nodule in the right medial frontal lobe, posterior to the surgical cavity. A 15 × 15 × 15 cm3 VOI was placed over the enhancing brain region. Spectrum (right) obtained with TE = 135 ms shows an increase in the Cho peak and a decrease in the NAA peak. The NAA/Cho ratio is 0.20.