FIG 2.

Brain MR images of a critically ill patient (Patient 2) with COVID-19 infection exhibiting impaired arousal, aphasia, and lethargy. A and B, Paired axial DWI and ADC map show symmetric foci of restricted diffusion involving the deep white matter of both cerebral hemispheres. C, Axial T2/FLAIR image through the same level shows associated increased T2/FLAIR hyperintensity corresponding to the regions of restricted diffusion. D, Axial fractional anisotropy map shows focal disruption of white matter tracts in the regions of diffusion restriction (white arrows). E and F, Paired axial DWI and ADC map show restricted diffusion of the body of the corpus callosum (arrow). G and H, Paired axial DWI and ADC map show restricted diffusion of the splenium of the corpus callosum (arrow).