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. 2020 Jul 28;9(9):882–889. doi: 10.1530/EC-20-0296

Table 2.

Integrated analyses results of the current meta-analysis.

Variables Sample size Dominant comparison Recessive comparison Over-dominant comparison Allele comparison
P-value OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value OR (95% CI)
ApaI rs7975232
 Overall 4693/4567 0.64 0.96 (0.83–1.12) 0.004 1.20 (1.06–1.37) 0.59 0.98 (0.89–1.07) 0.53 0.96 (0.85–1.09)
 Caucasian 1165/1637 0.007 0.77 (0.64–0.93) 0.11 1.31 (0.94–1.82) 0.85 0.98 (0.83–1.16) 0.04 0.81 (0.67–0.99)
 Asian 2091/1786 0.39 1.14 (0.85–1.52) 0.59 0.90 (0.61–1.32) 0.40 0.91 (0.72–1.14) 0.38 1.12 (0.87–1.45)
BsmI rs1544410
 Overall 4312/5015 0.002 0.77 (0.65–0.91) 0.0001 1.28 (1.13–1.45) 0.17 1.07 (0.97–1.18) 0.002 0.80 (0.70–0.92)
 Caucasian 1825/2388 0.002 0.69 (0.55–0.87) 0.08 1.29 (0.97–1.71) 0.05 1.14 (1.00–1.30) 0.008 0.78 (0.65–0.94)
 Asian 1297/1443 0.30 0.81 (0.54–1.21) 0.06 1.76 (0.98–3.17) 0.99 1.00 (0.79–1.27) 0.17 0.74 (0.48–1.14)
FokI rs10735810
 Overall 3612/3602 <0.0001 0.76 (0.69–0.84) 0.005 1.40 (1.11–1.78) 0.07 1.10 (0.99–1.21) 0.04 0.86 (0.75–0.99)
 Caucasian 889/847 0.30 0.90 (0.74–1.10) 0.89 1.02 (0.76–1.37) 0.08 1.19 (0.98–1.45) 0.71 1.04 (0.83–1.31)
 Asian 1358/1233 0.0001 0.61 (0.52–0.72) 0.001 2.02 (1.32–3.08) 0.18 1.12 (0.95–1.31) 0.002 0.68 (0.54–0.87)
TaqI rs731236
 Overall 2684/2956 0.57 0.94 (0.76–1.16) 0.13 1.13 (0.96–1.32) 0.67 1.04 (0.87–1.24) 0.93 0.99 (0.86–1.15)
 Caucasian 1208/1613 0.20 0.83 (0.62–1.10) 0.01 1.32 (1.06–1.63) 0.81 1.02 (0.87–1.20) 0.16 0.87 (0.73–1.05)
 Asian 350/277 0.33 1.24 (0.80–1.93) 0.79 0.89 (0.37–2.14) 0.77 0.89 (0.40–1.96) 0.06 1.42 (0.98–2.06)

The values in bold represent there is statistically significant differences between cases and controls.

NA, not available; OR, odds ratio.