Fig. 5.

Circ_0000282 promoted progress of OSA by regulating miR-192/XIAP Axis. a MiR-192 mimics or miR-192 inhibitors were transfected respectively into OSA cells with circ_0000282 overexpression or knockdown, and the expression level of miR-192 in OSA cells was detected by qRT-PCR. b-c The proliferation of OSA cells was detected by CCK-8 experiment and BrdU experiment. d Flow cytometry was used to detect the apoptosis of OSA cells. e qRT-PCR was used to detect the expression of XIAP mRNA. f Western blot was used to detect the expression of XIAP, Bcl-2 and Bax proteins in 143B cells and MG-63 cells. * denotes P < 0.05, ** denotes P < 0.01, and *** denotes P < 0.001