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. 2020 Oct 22;10:18074. doi: 10.1038/s41598-020-75029-1

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Exploring the effect of changing the similarity threshold: (a) the average number of retained features is shown as an increasing function in similarity threshold; and, (b) the average goodness-of-fit between the 50 PCs of both the original and reduced features is shown as a decreasing function in similarity threshold. This figure has been created using the Python library Matplotlib (version 3.3.0), available at https://matplotlib.org/users/installing.html.