Table 2.

Distribution of top haplotypes frequencies in 4 major supergroups^a

Haplotype (15 letters)	‘Tag’ haplotype	AFR	EAS	EUR	SAS
AGAAGGCGAGGGGAG	GG	0.562	0.86	0.605	0.642
GAGGCTTATAAAATA	AC	0.209	0.132	0.172	0.28
AGGGCTTATGAAATA	GC	0.043	0	0.21	0.045
SUM:		0.814	0.992	0.987	0.967

^a Supergroup denotations are given in Fig. 2. GWAS SNPs are marked with bold, eQTL causal SNP is marked in bold Cyrillic. The first allele is a major one (f > 0.5 in all supergroups), two others are minor ones. The ‘tag’ haplotype represents convoluted GWAS/eQTL 2-letter haplotype of tag SNPs (pos. 5:rs4658101, pos. 10:rs10874833). Two African–specific low frequency haplotypes AAGGCTTATGAAATA (0.099) and AAGGCTTATAAAATA (0.07) were omitted from consideration according to selection criterion