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. 2020 Oct 16;30(10):1470–1481. doi: 10.1089/thy.2020.0055

FIG. 7.

FIG. 7.

Heterozygous TERT mutant thyroid cancer cell lines exhibit higher levels of TERT transcript and telomerase activity compared with homozygous wild-type or mutant thyroid cancer cell lines. (A) TERT transcript level measured by quantitative reverse transcriptase-PCR in thyroid cancer cell lines, and (B) RTA in thyroid cancer cell lines compared with HEK293T cells. White denotes homozygous wild type (stippling denotes the TERT homozygous wild-type cancer cell line from the normal thyroid cell line), gray denotes heterozygous mutant, and black denotes homozygous mutant thyroid cancer cell lines. Standard deviation is noted. RTA, relative telomerase activity.