Table 2.

Comparison of Results with and without Dementia Included: Lifetime Cost Effectiveness of NHS DPP v. No Implementation of NHS DPP

	No Dementia		Dementia Only		Reduced Dementia Risk
Absolute Results	No DPP	DPP	No DPP	DPP	No DPP	DPP
Net benefit (£20,000 willingness to pay)	186,525	186,525	180,904	181,771	180,904	182,074
Health and social care cost (per person)	26,870	26,725	30,134	30,013	30,134	29,967
Health care cost (per person)	25,032	24,909	25,604	25,493	25,604	25,511
Social care cost (per person)	1838	1816	4530	4520	4530	4455
Dementia cost (per person)	NA	NA	1172	1177	1172	1146
Cardiovascular cost (per person)	6550	6453	6361	6266	6361	6289
QALYs (per person)	10.67	10.71	10.55	10.59	10.55	10.60
Life years (per 1000 people)	24.17	24.24	23.74	23.80	23.74	23.84
Diabetes diagnoses (per 1000 people)	663	651	657	646	657	647
CVD events (per 1000 people)	456	453	446	443	446	445
Dementia diagnosis (per 1000 people)	231	232	242	243	242	238
			Targeting Strategy (Incremental Results v. Do Nothing)
Incremental Results for DPP v. No DPP		No Dementia	Dementia Only	Difference from No Dementia	Reduced Dementia Risk	Difference from No Dementia
Incremental net benefit (£20,000 willingness to pay)		£1000	£987	–£13	£1290	£291
Incremental health and social care cost (per person)		–£145	–£121	£24	–£167	–£22
Incremental health care cost (per person)		–£123	–£111	£12	–£93	£30
Incremental social care cost (per person)		–£23	–£10	£13	–£75	–£52
Incremental dementia cost (per person)		0	£5	£5	–£26	–£26
Incremental cardiovascular cost (per person)		–£97	–£95	£2	–£72	£25
Incremental QALYs (per person)		0.0427	0.0433	0.0006	0.0562	0.0134
Incremental life years (per person)		0.0635	0.0665	0.0030	0.1003	0.0368
Incremental diabetes diagnoses (per 1000 people)		−11	−11	0	−10	1
Incremental CVD events (per 1000 people)		−3	−3	0	−1	1
Incremental dementia diagnosis (per 1000 people)		0	1	1	−4	−4

CVD, cardiovascular disease; DPP, diabetes prevention program; NHS, National Health Service; QALY, quality-adjusted life year.