Table 1. Demographic Characteristics of the Participants, According to Vaccine Candidate and Age Group.*.
| Variable | Participants 18–55 Years of Age | Participants 65–85 Years of Age | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 10 μg | 20 μg | 30 μg | 100 μg | Placebo | Total | 10 μg | 20 μg | 30 μg | Placebo | Total | |
| BNT162b1 | |||||||||||
| No. of participants | 12 | 12 | 12 | 12 | 12 | 60 | 12 | 12 | 12 | 9 | 45 |
| Sex — no. (%) | |||||||||||
| Male | 7 (58) | 9 (75) | 6 (50) | 5 (42) | 7 (58) | 34 (57) | 4 (33) | 4 (33) | 4 (33) | 1 (11) | 13 (29) |
| Female | 5 (42) | 3 (25) | 6 (50) | 7 (58) | 5 (42) | 26 (43) | 8 (67) | 8 (67) | 8 (67) | 8 (89) | 32 (71) |
| Race — no. (%)† | |||||||||||
| White | 8 (67) | 11 (92) | 10 (83) | 11 (92) | 11 (92) | 51 (85) | 12 (100) | 11 (92) | 10 (83) | 9 (100) | 42 (93) |
| Black | 1 (8) | 1 (8) | 0 | 0 | 0 | 2 (3) | 0 | 1 (8) | 0 | 0 | 1 (2) |
| Asian | 3 (25) | 0 | 2 (17) | 1 (8) | 1 (8) | 7 (12) | 0 | 0 | 2 (17) | 0 | 2 (4) |
| Hispanic ethnic group — no. (%)† | 1 (8) | 0 | 1 (8) | 0 | 0 | 2 (3) | 0 | 0 | 0 | 1 (11) | 1 (2) |
| Age — yr‡ | |||||||||||
| Mean | 29.4±6.4 | 44.8±8.3 | 35.8±10.0 | 38.3±9.3 | 36.3±11.3 | 36.9±10.2 | 69.7±5.4 | 70.6±4.9 | 69.9±3.6 | 68.2±3.0 | 69.7±4.3 |
| Median (range) | 26.5 (24–42) |
49.0 (30–54) |
33.5 (23–52) |
38.0 (25–53) |
35.0 (19–54) |
35.0 (19–54) |
68.5 (65–82) |
69.0 (65–81) |
69.0 (65–77) |
68.0 (65–73) |
69.0 (65–82) |
| BNT162b2 | |||||||||||
| No. of participants | 12 | 12 | 12 | 0 | 9 | 45 | 12 | 12 | 12 | 9 | 45 |
| Sex — no. (%) | |||||||||||
| Male | 5 (42) | 6 (50) | 3 (25) | — | 5 (56) | 19 (42) | 2 (17) | 5 (42) | 6 (50) | 4 (44) | 17 (38) |
| Female | 7 (58) | 6 (50) | 9 (75) | — | 4 (44) | 26 (58) | 10 (83) | 7 (58) | 6 (50) | 5 (56) | 28 (62) |
| Race — no. (%)† | |||||||||||
| White | 11 (92) | 10 (83) | 9 (75) | — | 9 (100) | 39 (87) | 12 (100) | 12 (100) | 12 (100) | 9 (100) | 45 (100) |
| Black | 0 | 2 (17) | 1 (8) | — | 0 | 3 (7) | 0 | 0 | 0 | 0 | 0 |
| Asian | 1 (8) | 0 | 2 (17) | — | 0 | 3 (7) | 0 | 0 | 0 | 0 | 0 |
| Hispanic ethnic group — no. (%)† | 1 (8) | 1 (8) | 0 | — | 0 | 2 (4) | 0 | 0 | 0 | 0 | 0 |
| Age — yr‡ | |||||||||||
| Mean | 36.8±12.2 | 37.6±10.1 | 37.3±9.8 | — | 34.4±13.2 | 36.7±11.0 | 68.0±2.9 | 71.0±5.8 | 68.5±2.8 | 70.0±3.8 | 69.3±4.1 |
| Median (range) | 37.0 (21–53) |
38.0 (23–53) |
36.5 (23–54) |
— | 30.0 (19–53) |
37.0 (19–54) |
67.0 (65–73) |
68.5 (65–81) |
68.0 (65–74) |
69.0 (65–77) |
68.0 (65–81) |
*
Plus–minus values are means ±SD. Percentages may not total 100 because of rounding.
†
Race and ethnic group were reported by the participant.
‡
The age of the participants was the age at the time of the injection.