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. 2020 Oct 9;11:564140. doi: 10.3389/fphys.2020.564140

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Copyright © 2020 Imam, Winnebeck, Buchholz, Froguel, Bonnefond, Solimena, Ivanova, Bouvier, Plouffe, Charpentier, Karamitri, Jockers, Roenneberg and Vetter.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Sleep onset, (B) midsleep, (C) Sleep Regularity Index (SRI), (D) Composite phase deviation (CPD), (E) first caloric intake to average sleep offset CPD; (F) caloric intake frequency; (N = 28) across groups. Pirate plots show median (bar), 25–75th percentile (box) and density of raw data not adjusted for age and sex. T2D controls, Type 2 diabetic control patients; T2D MT₂, T2D patients with rare MT₂ receptor variants.