TABLE 3.

Regression analyses of sleep and circadian phenotypes (N = 28).

	T2D (n = 14)	T2D MT2 (n = 14)	T2D vs. T2D MT2. p-value
Twenty-four-hour sleep duration (h)	0.00 (ref)	−0.82 (−1.84;0.20)	0.13
Main episode sleep duration (h)	0.00 (ref)	−0.76 (−1.97;0.44)	0.23
Sleep onset (h)	0.00 (ref)	1.23 (0.42;2.04)	< 0.01
Sleep offset (h)	0.00 (ref)	0.47 (−0.66;1.59)	0.42
Midsleep (h)	0.00 (ref)	0.91 (0.12;1.70)	0.03
Sleep Regularity Index	0.00 (ref)	−8.98 (−16.36;−1.60)	0.03
Composite phase deviation	0.00 (ref)	1.21 (0.51;1.92)	< 0.01
Fasting duration (h)	0.00 (ref)	0.11 (−0.83;1.05)	0.82
First caloric intake (h)	0.00 (ref)	0.41 (−0.35;1.18)	0.30
Last caloric Intake (h)	0.00 (ref)	0.38 (−0.15;0.91)	0.16
Midpoint caloric intake window (h)	0.00 (ref)	0.39 (−0.07;0.86)	0.11
Caloric intake timing CPD	0.00 (ref)	0.30 (−0.22;0.81)	0.27
First caloric intake to average sleep offset CPD	0.00 (ref)	1.08 (0.07;2.08)	0.046
Last caloric intake to average sleep onset CPD	0.00 (ref)	0.89 (0.03;1.75)	0.054
Δ first caloric intake to sleep offset (h)	0.00 (ref)	0.55 (−0.43;1.53)	0.28
Δ last caloric intake to sleep onset (h)	0.00 (ref)	0.85 (0.03;1.67)	0.052
Caloric intake frequency	0.00 (ref)	1.08 (0.26;1.90)	0.02
Snack intake frequency	0.00 (ref)	0.03 (−0.41;0.47)	0.88

We report age- and sex-adjusted mean differences including 95% confidence intervals (95%CIs). T2D, Type 2 diabetic control patients; T2D MT₂, T2D patients with rare MT₂ receptor variants.