Table 1.
Treatment (mg/kg) | Renal Damage Score (6 Kidneys/Group × 6 Slices/Kidney) | ± S.D. | ||||
---|---|---|---|---|---|---|
0 | 1 | 2 | 3 | 4 | ||
Control | 30 | 6 | 0 | 0 | 0 | 0.67 ± 0.48 |
LPS | 0 | 0 | 0 | 15 | 21 | 3.58 ± 0.50 a3 |
Simvastatin 10 group | 0 | 0 | 12 | 24 | 0 | 2.67 ± 0.48 a1 |
Simvastatin 20 group | 0 | 0 | 24 | 12 | 0 | 2.33 ± 0.47 a1 |
Simvastatin 40 group | 0 | 21 | 15 | 0 | 0 | 1.42 ± 0.50 b2 |
Statistical analysis was performed using the Kruskal–Wallis test. a1, a3—p < 0.05, 0.001 in comparison to the control group, b2—p < 0.01 in comparison to the LPS-only treated group. (—mean value, S.D—standard deviation).