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6-Methoxymellein suppresses the secretion and transcription of IL-6 and IL-8. (A) The CBA Human Inflammatory Cytokine Assay Kit was used to assay the secretion of cytokines in mammosphere culture media treated with 6-methoxymellein or DMSO. (B) Transcript levels of the IL-6 and IL-8 genes were assessed in 6-methoxymellein-treated mammospheres using specific RT-qPCR primers. Our data are represented as the mean ± SD. ** p < 0.05 and *** p < 0.01 versus the control group.
