Figure 1.

Effects of sauchinone on renal mesangial cell proliferation. Human mesangial cells were treated with angiotensin II (AngII) (10 μM) and incubated with or without sauchinone (from 0, 0.1, and 1 μM) for 48 h. (A) Cell number results of mesangial cells using Countess™ cell counting, (B) cell proliferation results using [³H]-thymidine incorporation assay, (C) results of mesangial cell index using xCELLigence RTCA DP Real time cell analyzer, and (D) quantification results of mesangial cell Index (fold of control). Results are expressed as the mean ± S.E. from four independent experiments. ** p < 0.01 vs. control; # p < 0.05, and ## p < 0.01 vs. AngII alone.