Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 30;21(19):7252. doi: 10.3390/ijms21197252

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Microglial cell activation in transplanted P23H-1 rats. Microphotographs of representative retinal cross-sections taken from control Sprague-Dawley (SD) rats (A), and the right untreated eyes (B) and left treated eyes (C–J) of P23H-1 rats that received IVI (C–F) or SRI (G–J) of hBM-MSCs. Immunostained microglial cells (green; rabbit anti-Iba1 antibody) and also DAPI counterstaining (blue) of the retinas can be observed at different time periods after the injection. Graphs show the mean numbers ± SD of Iba-1+cells in the retina of control SD rats (black bars; include data from both right and left eyes) and in the right uninjected eyes (blue bars) and left eyes (red bars) of P23H-1 rats that received IVI (K) or SRI (L) of hBM-MSCs. No significant differences were observed between right and left eyes at any period. n=6 eyes for control group and treated eyes group at all time points studied; n=12 eyes for untreated eyes group at all time points studied. Scale bar: 100 µm. GCL= ganglion cells layer; INL= inner nuclear layer; OSL= photoreceptors outer segment layer.