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. 2020 Sep 29;21(19):7176. doi: 10.3390/ijms21197176

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Histological characterization of HCM myectomy tissues (A) Histological characterization of HCM tissues compared to control tissues using hematoxylin and eosin (H&E) staining, WGA staining, Picro-sirius staining, and TGFβ1 expression, assessed by immunohistochemistry. Scale bars are 100 (overview) and 20 µm (magnified insets). (B) Bar plots show a significant increase of cardiomyocytes size (µm²) (6 HCM vs. 3 ctrls), interstitial fibrosis index (79 HCM vs. 9 ctrls), and TGFβ1 levels (79 HCM vs. 9 ctrls).