Figure 1.

Renal outcome measures in mother rats. (A) Body weights, (B) plasma creatinine level, (C) kidney weight-to-body weight ratio, (D) systolic blood pressures, (E) periodic acid-Schiff stained sections demonstrating renal histopathology of female rats fed with regular chow (control) or chow supplemented with 0.5% adenine (chronic kidney disease, CKD) for 3 weeks before pregnancy; scale bar = 30 μm, (F) glomerular injury score, and (G) tubulointerstitial injury score. Data are shown as means ± SD; n = 8/group. The asterisk indicates p < 0.05 vs. control.