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. 2020 Oct 7;25(19):4572. doi: 10.3390/molecules25194572

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Small molecule inhibitors targeting the ATPase Activity of NLRP3. Chemical structures of NLRP3 Inhibitors which target the ATPase activity of NLRP3 are provided. The molecular structures were generated in ChemDraw v19, and the Michael acceptor moiety is coloured in red for electrophilic inhibitors. PubChem Compound Identification Numbers: MCC950, 9910393; parthenolide, 7251185; Bay11-7082, 5353431; CY-09, 75070350; MNS, 672296; OLT1177, 12714644; Bot-4-one, 16129399; and INF39, 69150705.