Table 3. Factors affecting recurrence-free survival by Cox's proportional hazards regression model analyses.
| Items | Univariate Cox's regression | Multivariate Cox's regression | ||
|---|---|---|---|---|
| P value | HR (95%CI) | P value | HR (95%CI) | |
| lnc-MALAT1 (high vs low) | 0.062 | 0.402 (0.154–1.047) | 0.200 | 0.482 (0.157–1.473) |
| Age (≥61 vs <61 years) | 0.976 | 0.986 (0.406–2.397) | 0.974 | 0.981 (0.307–3.137) |
| Gender (male/female) | 0.853 | 1.095 (0.421–2.850) | 0.965 | 0.974 (0.304–3.120) |
| BMI (≥24.2 vs <24.2 kg/m2) | 0.506 | 0.741 (0.307–1.791) | 0.725 | 0.835 (0.305–2.282) |
| Smoking (yes vs no) | 0.456 | 0.712 (0.291–1.741) | 0.509 | 0.726 (0.281–1.876) |
| Hypertension (yes vs no) | 0.836 | 1.167 (0.270–5.047) | 0.704 | 1.371 (0.269–6.980) |
| Diabetes mellitus (yes vs no) | 0.193 | 0.378 (0.088–1.633) | 0.526 | 0.585 (0.111–3.075) |
| Hyperlipidemia (yes vs no) | 0.853 | 0.920 (0.380–2.227) | 0.978 | 1.015 (0.365–2.821) |
| Hyperuricemia (yes vs no) | 0.958 | 1.026 (0.394–2.673) | 0.712 | 0.819 (0.283–2.370) |
| CKD (yes vs no) | 0.821 | 1.136 (0.377–3.418) | 0.609 | 1.435 (0.360–5.728) |
| NIHSS score (≥7 vs <7) | 0.428 | 0.701 (0.292–1.687) | 0.229 | 0.557 (0.215–1.445) |
| CRP (≥29.0 vs <29.0 mg/L) | 0.006 | 4.683 (1.563–14.028) | 0.024 | 4.720 (1.224–18.197) |
| TNF-α (≥60.1 vs <60.1 pg/mL) | 0.126 | 2.052 (0.818–5.151) | 0.350 | 1.879 (0.501–7.041) |
| IL-6 (≥44.7 vs <44.7 pg/mL) | 0.301 | 1.605 (0.655–3.931) | 0.899 | 1.069 (0.381–2.996) |
| IL-8 (≥50.4 vs <50.4 pg/mL) | 0.988 | 0.993 (0.413–2.387) | 0.387 | 0.559 (0.149–2.088) |
| IL-10 (≥20.9 vs <20.9 pg/mL) | 0.133 | 0.493 (0.196–1.239) | 0.548 | 0.707 (0.227–2.195) |
| IL-17 (≥96.2 vs 96.2 pg/mL) | 0.586 | 0.783 (0.324–1.889) | 0.153 | 0.474 (0.170–1.319) |
| IL-22 (≥67.8 vs <67.8 pg/mL) | 0.299 | 1.608 (0.656–3.942) | 0.716 | 0.797 (0.235–2.705) |
HR: hazard ratio; CI: confidence interval; BMI: body mass index; CKD: chronic kidney disease; NIHSS: National Institutes of Health Stroke Scale; CRP: C-reactive protein; TNF-α: tumor necrosis factor α; IL: interleukin. Significant P values are shown in bold.