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. 2020 Oct 23;15(10):e0240209. doi: 10.1371/journal.pone.0240209

Table 6. Accuracy of the PHQ-9 cut-off values for detecting any depression disorder (diagnosed with the MINI) in adults with diabetes for the Polish sample (N = 216).

PHQ-9 raw score cut-off Sensitivity Specificity Positive Predictive Value Negative Predictive Value Positive likelihood ratio Negative likelihood ratio Youden's index
≥ 0 1.00 0.00 0.16 - (*) 1.00 - (*) 0.00
≥ 1 1.00 0.20 0.19 1.00 1.25 0.00 0.20
≥ 2 1.00 0.37 0.23 1.00 1.58 0.00 0.37
≥ 3 1.00 0.56 0.30 1.00 2.28 0.00 0.56
≥ 4 1.00 0.69 0.37 1.00 3.19 0.00 0.69
≥ 5 b) 0.94 0.79 0.45 0.99 4.39 0.07 0.73
≥ 6 0.88 0.85 0.53 0.97 5.95 0.14 0.73
≥ 7 a) 0.85 0.90 0.62 0.97 8.62 0.16 0.75
≥ 8 0.79 0.92 0.64 0.96 9.64 0.22 0.71
≥ 9 0.79 0.94 0.71 0.96 13.14 0.22 0.73
≥ 10 c) 0.65 0.96 0.73 0.94 14.72 0.37 0.60
≥ 11 0.62 0.96 0.72 0.93 14.05 0.40 0.57
≥ 12 0.59 0.97 0.77 0.93 17.84 0.43 0.56
≥ 13 0.44 0.98 0.83 0.90 26.76 0.57 0.42
≥ 14 0.41 0.99 0.88 0.90 37.47 0.59 0.40
≥ 15 0.29 0.99 0.91 0.88 53.53 0.71 0.29
≥ 16 0.29 0.99 0.91 0.88 53.53 0.71 0.29
≥ 17 0.29 1.00 1.00 0.88 - (*) 0.71 0.29
≥ 18 0.29 1.00 1.00 0.88 - 0.71 0.29
≥ 19 0.24 1.00 1.00 0.88 - 0.76 0.24
≥ 20 0.15 1.00 1.00 0.86 - 0.85 0.15
≥ 21 0.06 1.00 1.00 0.85 - 0.94 0.06
≥ 22 0.06 1.00 1.00 0.85 - 0.94 0.06
≥ 23 0.06 1.00 1.00 0.85 - 0.94 0.06
≥ 24 0.06 1.00 1.00 0.85 - 0.94 0.06
≥ 25 0.03 1.00 1.00 0.85 - 0.97 0.03
≥ 26 0.03 1.00 1.00 0.85 - 0.97 0.03
= 27 0.03 1.00 1.00 0.85 - 0.97 0.03

Note.

(*) If the sample sizes in the positive (Disease present) and the negative (Disease absent) groups do not reflect the real prevalence of the disease, then the Positive and Negative predicted values, and Accuracy, cannot be estimated and you should ignore those values.

a) Optimal cut-off scores according to maximal Youden Index (sensitivity+specificity−1).

b) Recommended cut-off scores for a two-stage screening (maximal sensitivity and ≥75% specificity).

c) Generally recommended cut-off score.