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. 2020 Oct 23;15(10):e0240926. doi: 10.1371/journal.pone.0240926

Table 1. Sociodemographic variables and comorbidities.

TOTAL n = 153 30-day mortality p*
ALIVE n = 135 DECEASED n = 18
% n % n % n
Age—mean / SD 75.68 16.13 73.82 16.18 89.69 5.15 <0.001
Gender (male) 58.17 89 58.52 79 55.56 10 0.811
Ethnicity (caucasian) 97.39 149 97.04 131 100 18 1.000
Life habits and vaccination
Alcoholism (active o former) 8.50 13 8.89 12 5.56 1 1.000
Tobacco use (active o former) 65.10 99 65.93 89 58.82 10 0.563
Pack-years—mean / SD 27.24 29.66 27.17 29.37 27.86 33.38 0.935
Pneumococcal vaccination 41.33 62 40.60 54 47.06 8 0.611
Flu vaccination (previous year) 62.00 93 62.41 83 58.82 10 0.774
Comorbidities
HBP 58.17 89 59.26 80 50.00 9 0.454
DM 16.34 25 17.04 23 11.11 2 0.739
Hypercholesterolemia 32.68 50 30.37 41 50.00 9 0.095
Obesity 42.48 65 42.96 58 38.89 7 0.743
TIA 4.58 7 3.7 5 11.11 2 0.192
Stroke 11.76 18 9.63 13 27.78 5 0.041
Ischemic cardiomyopathy 8.5 13 7.41 10 16.67 3 0.183
Chronic heart failure 18.95 29 18.52 25 22.22 4 0.750
VTE 1.96 3 1.48 2 5.56 1 0.315
CKD 14.38 22 14.81 20 11.11 2 1.000
Chronic hapatopathy 3.27 5 3.7 5 0.00 0 0.406
COPD 31.37 48 31.85 43 27.78 5 0.794
Asthma 5.23 8 5.93 8 0.00 0 0.597
HIV infection 5.88 9 6.67 9 0.00 0 0.600
Solid neoplasm 9.15 14 8.15 11 16.67 3 0.216
Modified Charlson Index—mean / SD 3.12 2.94 2.98 2.98 4.22 2.39 0.092
Chronic treatment
Bronchodilators (any type) 33.33 51 34.07 46 27.78 5 0.791
Oral corticosteroids 3.97 6 3.73 5 5.88 1 0.518
Statins 29.14 44 28.36 38 35.29 6 0.553
Antiplatelets 26.14 40 25.19 34 33.33 6 0.460
Functional status
Institutionalized 7.84 12 5.93 8 22.22 4 0.037
Cognitive impairment 17.65 27 11.85 16 61.11 11 <0.001
Malnutrition 11.11 17 9.63 13 22.22 4 0.119
History of bronchoaspiration 8.5 13 4.44 6 38.89 7 <0.001

CKD: Chronic kidney disease; COPD: Chronic obstructive pulmonary disease; DM: Diabetes mellitus; HBP: High blood pressure; HIV: Human immunodeficiency virus; TIA: Transient ischemic attack; VTE: Venous thromboembolism.

Quantitative variables: Mean and SD; Qualitative variables: % and n;

* Qualitative variables: Chi-square test or Fisher´s exact test. Quantitative variables: t-test for equal or unequal variances as appropriate.