Table 1. Demographic, clinical, and cognitive screen data for PREVENT subjects.
| Characteristics | TIA, n = 95 | Non-TIA, n = 51 | P values |
|---|---|---|---|
| Age, years (Mean±SD) | 67.9 ± 9.4 | 64.9 ± 9.9 | 0.07 |
| Sex, female | 47% | 67% | 0.32 |
| DWI lesions (% of subjects) | 25 (26%) | N/A | NA |
| Mean DWI lesion volume, mL (±SD) | 0.63 ± 0.87 | N/A | N/A |
| NART (Verbal IQ; Intellect) (Mean±SD) | 106.6 ± 9.6 | 109.6 ± 8.7 | 0.07 |
| FRS, n | Low: 14 (14.7%) | Low: 25 (49.0%) | 0.02 |
| Moderate: 20 (21.1%) | Moderate: 16 (31.4%) | ||
| High: 52 (54.7%) | High: 9 (17.6%) | ||
| N/A: 9 (9.5%) | N/A: 1 (2.0%) | ||
| ICV, mL (Mean±SD) | 1394.7 ± 123.5 | 1374.8 ± 122.7 | 0.36 |
| WM hyperintensities volume, mL (Mean±SD) | 11.4 ± 13.1 | 9.1 ± 10.9 | 0.28 |
| Stroke Etiology | N/A | ||
| Atrial Fibrillation | 9 (9.5%) | ||
| Cardioembolic | 2 (2.1%) | ||
| Cryptogenic | 53 (55.8%) | ||
| Hypotension | 1 (1.1%) | ||
| ICAD | 1 (1.1%) | ||
| Large Artery | 6 (6.3%) | ||
| Large Vessel | 1 (1.1%) | ||
| Migraine Aura | 3 (3.2%) | ||
| Migraine | 3 (3.2%) | ||
| Peripheral Vertigo | 1 (1.1%) | ||
| Small Vessel | 15 (15.8%) | ||
| ACE-R | |||
| Median (IQR) | 91 (86–96) | 95 (91–97.8) | <0.01 |
| MoCA | |||
| Median (IQR) | 26 (23–27) | 27 (25–28.8) | 0.29 |
| MMSE | |||
| Median (IQR) | 30 (28–30) | 30 (30–30) | 0.64 |
IQR: interquartile range, 25th and 75th percentiles were presented; DWI: Diffusion-weighted imaging; NART: National Adult Reading Test; FRS: Framingham Risk Score (FRS); ICV: Intracranial volume; WM: White matter; ICAD: Intracranial Atherosclerotic Disease; ACE-R: Addenbrooke’s Cognitive Assessment-Revised; MoCA: Montreal Cognitive Assessment; MMSE: Mini-Mental State Examination.