Table 3. Linear mixed-effects regression analysis for FA and MD controlling for age, sex, premorbid intellect, Framingham Risk Score (FRS), intracranial volume (ICV), WM hyperintensities volume, and the interaction of FA and MD with group (TIA subjects and non-TIA subjects).
| FA | MD | |||
|---|---|---|---|---|
| Estimate (95%CI) | P | Estimate (95% CI) | P | |
| TIA vs. Non-TIA | TIA vs. Non-TIA | |||
| CG | -0.05 [-0.23–0.13] | 0.578 | 0.06 [-0.05–0.17] | 0.292 |
| PHC | -0.07 [-0.24–0.11] | 0.441 | 0.01 [-0.10–0.11] | 0.936 |
| Fornix | -0.16 [-0.34–0.01] | 0.069 | 0.36 [0.26–0.47] | <0.001 |
| SLF | -0.29 [-0.46- -0.11] | 0.001 | 0.03 [-0.08–0.14] | 0.598 |
| UF | -0.26 [-0.43 - -0.08] | 0.004 | 0.03 [-0.08–0.14] | 0.603 |
| Genu | -0.22 [-0.39- - 0.04] | 0.016 | 0.04 [-0.07–0.15] | 0.453 |
The coefficients reported were standardized. SE: standard error; FRS: Framingham Risk Score; ICV: Intracranial Volume; CG: Cingulum Gyrus; PHC: Parahippocampal Cingulum; SLF: Superior Longitudinal Fasciculus; UF: Uncinate Fasciculus.