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. 2020 Oct 20;11(42):3770–3781. doi: 10.18632/oncotarget.27776

Figure 3. Effects of Cisplatin and PolyHb on cell viability and cytotoxicity.

Figure 3

(TOP) Shift in cisplatin sensitivity in (A) H23, (B) H460, and (C) A549 cell lines upon addition of 0.1 or 0.2 g/dL of PolyHb. Curves represent the mean percentage of viable cells (mean ± SD) relative to 0 μM cisplatin (n = 5 total). (BOTTOM) Cisplatin cytotoxicity in (D) H23, (E) H460, and (F) A549 cell lines upon addition of 0.1 or 0.2 g/dL of PolyHb (mean ± SD, n = 5). The cisplatin dose was 0.2 μM in all groups treated for 48 h. *significant with respect to the control group; †significant with respect to the cisplatin-only group; ‡significant with respect to the cisplatin + PolyHb (0.1 g/dL) group.