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. 2020 Oct 13;16(10):e1009087. doi: 10.1371/journal.pgen.1009087

Fig 2. Explanatory power of varying MeCP2 levels (in vitro and in vivo).

Fig 2

(A) Fraction of variance explained by regressing splicing variation against sequence features combined with MeCP2 binding in cultured human neurons [9]. (B) Fraction of variance explained by regressing splicing variation against sequence features combined with changes in DNA methylation in WT and MeCP2 KO mouse brain [17].