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. 2020 Oct 13;18(10):e3000829. doi: 10.1371/journal.pbio.3000829

Table 3. Overview.

Relationships between GPi and VLa
Hypothesized versus observed
Gating
[15; 41]
Rebound
[18; 22]
Observed
Incidence of increase- versus decrease-type responses Inverted. GPi increases proportional to VLa decreases Direct. GPi increases proportional to VLa increases Direct. Similar rates of increases found in GPi and VLa (see Table 1)
Timing of movement-related responses GPi leads VLa by about 2 ms GPi leads VLa by about 100 ms GPi lags VLa by about 43 ms (see Fig 3A)
GPi-VLa spike-spike CCFs Negative CCF peaks at short latency in subpopulation of pairs CCF peaks negative at short latency followed by positive at long latency. CCF peaks are rare (at noise rate). No net bias toward negative or positive peaks (see Fig 4A–4F and Table 2)
GPi-VLa FR correlations (NCs) Negative NCs are larger and/or more common Positive NCs are larger and/or more common Significant NCs are rare w/ no net bias toward positive or negative relationships (see Fig 4G–4H and Table 2)
VLa FR following burst in GPi firing VLa FR decreases at short latency (about 2 ms) VLa FR decreases following burst onset Long-lasting (>200 ms) VLa decrease w/ pause part of GPi burst-pause complex (see Fig 5)
VLa FR following pauses in GPi firing VLa FR increases at short latency (about 2 ms) VLa FR increases at short latency

Abbreviations: CCF, cross-correlation function; FR, firing rate; GPi, globus pallidus-internus; NC, noise correlation; VLa, ventrolateral anterior nucleus; w/, with