Table 1.
Amino acids having a role in the interaction of hACE-2 with SARS-CoV-2-CTD and SARS-CoV-RBD18.
| hACE-2 | SARS-CoV-2-CTD | SARS-CoV-RBD |
|---|---|---|
| S19 | A475, G476 | P462 |
| Q24 | A475, G476, N478 | N473 |
| T27 | F456, Y473, A475, Y489 | L443, Y475 |
| F28 | Y489 | Y475 |
| D30 | K417, L455, F456 | Y442 |
| K31 | L455, F456, E484, Y489, F490, Q493 | Y442, Y475 |
| H34 | Y453, L455, Q493 | Y440, Y442, N479 |
| E35 | Q493 | - |
| E37 | Y505 | Y491 |
| D38 | Y449, G496, Q498 | Y436, G482, Y484 |
| Y41 | Q498, T500, N501 | Y484, T486, T487 |
| Q42 | G446, Y449, Q498 | Y436, Y484 |
| L45 | Q498, T500 | Y484, T486 |
| L79 | F486 | L472 |
| M82 | F486 | L472 |
| Y83 | F486, N487, Y489 | N473, Y475 |
| Q325 | - | R426 |
| E329 | - | R426 |
| N330 | T500 | T486 |
| K353 | G496, N501, G502, Y505 | Y481, G482, Y484, T487, G488, Y491 |
| G354 | Y502, Y505 | G488, Y491 |
| D355 | T500, G502 | T486, T487, G488 |
| R357 | T500 | T486 |
| R393 | Y505 | Y491 |