Table 6.
Effects of taurine supplementation on antioxidant gene expression in the liver of LPS-challenged broilers1
| Treatment2 | |||||
|---|---|---|---|---|---|
| Item3 | CON | LPS | LPS + T1 | LPS + T2 | P-value |
| Nrf2 | 1.00 ± 0.06a | 0.70 ± 0.04b | 0.93 ± 0.06a | 0.90 ± 0.05a | 0.003 |
| HO-1 | 1.00 ± 0.10a | 0.71 ± 0.07b | 0.99 ± 0.09a | 1.03 ± 0.09a | 0.060 |
| SOD1 | 1.00 ± 0.04a | 0.71 ± 0.04b | 0.92 ± 0.11ab | 0.83 ± 0.08ab | 0.061 |
| GSH-Px | 1.00 ± 0.06a | 0.74 ± 0.05b | 0.91 ± 0.03a | 0.93 ± 0.05a | 0.004 |
| GCLC | 1.00 ± 0.13a | 0.63 ± 0.04b | 1.22 ± 0.15a | 1.23 ± 0.08a | 0.001 |
| GCLM | 1.00 ± 0.14 | 1.02 ± 0.10 | 1.12 ± 0.06 | 1.08 ± 0.12 | 0.869 |
1Data are means ± SEM, n = 8.
2CON, control basal diet; LPS, LPS challenged broilers fed CON; LPS+T1, LPS challenged broilers fed CON supplemented with 5 g/kg taurine; LPS+T2, LPS challenged broilers fed CON supplemented with 7.5 g/lg taurine.
3Expressed in arbitrary units. The expression of each target gene for the CON group was assigned a value of 1 and normalized against beta-actin.
a,bMeans within the same row with no common superscript differ significantly (P < 0.05).