Table 8.
Effects of ETEC infection on bacterial genera of ascending colon contents at 10 DPI in weanling pigs1
| Phylum | Family | Genus | Log2 fold-change PC/NC | P adj | Shift |
|---|---|---|---|---|---|
| Firmicutes | Ruminococcaceae | Oscillospira | 8.05 | <0.001 | Increase |
| Proteobacteria | Burkholderiaceae | Sutterella | 4.73 | 0.010 | Increase |
| Proteobacteria | Succinivibrionaceae | Succinivibrio | 4.52 | <0.001 | Increase |
| Firmicutes | Ruminococcaceae | Ruminiclostridium 9 | 3.84 | 0.001 | Increase |
| Firmicutes | Acidaminococcaceae | Phascolarctobacterium | 2.71 | 0.010 | Increase |
| Bacteroidetes | Muribaculaceae | Uncultured | 1.95 | 0.010 | Increase |
| Firmicutes | Lachnospiraceae | Oribacterium | –2.02 | 0.062 | Decrease |
| Firmicutes | Veillonellaceae | Dialister | –2.64 | 0.010 | Decrease |
| Firmicutes | Streptococcaceae | Streptococcus | –2.79 | 0.016 | Decrease |
| Firmicutes | Erysipelotrichaceae | Catenibacterium | –2.95 | 0.037 | Decrease |
| Firmicutes | Erysipelotrichaceae | Catenisphaera | –5.31 | 0.014 | Decrease |
| Firmicutes | Veillonellaceae | Unclassified | –6.51 | 0.042 | Decrease |
| Firmicutes | Lachnospiraceae | Lachnospiraceae NK3A20 group | –6.81 | 0.009 | Decrease |
1Data derived from 6 to 7 pigs per treatment and analyzed using the DESeq2 package of R. All pigs were started on their assigned dietary treatment starting at –10 DPI. Experimental treatments: NC, sham-inoculated pigs receiving 1.0% wild-type algal protein; PC, ETEC-inoculated pigs receiving 1.0% wild-type algal protein. Abbreviations: ETEC, enterotoxigenic E. coli; Padj, P-value adjusted by the Benjamini–Hochberg method to control for false discovery rate.