Table 9.
Effects of dietary algal protein supplementation during ETEC-infection on bacterial genera of ascending colon contents at 10 DPI in weanling pigs1
| Phylum | Family | Genus | Log2 fold-change OA/PC | P adj | Shift |
|---|---|---|---|---|---|
| Firmicutes | Streptococcaceae | Streptococcus | 3.44 | 0.032 | Increase |
| Firmicutes | Lachnospiraceae | Blautia | 1.36 | 0.081 | Increase |
| Bacteroidetes | Rikenellaceae | Rikenellaceae RC9 gut group | –1.86 | 0.035 | Decrease |
| Bacteroidetes | Muribaculaceae | Uncultured | –2.27 | 0.062 | Decrease |
| Bacteroidetes | Prevotellaceae | Prevotella 2 | –2.72 | 0.041 | Decrease |
| Bacteroidetes | Prevotellaceae | Prevotella 7 | –3.81 | 0.008 | Decrease |
| Bacteroidetes | Prevotellaceae | Prevotella 1 | –2.58 | 0.062 | Decrease |
| Proteobacteria | Burkholderiaceae | Sutterella | –5.10 | 0.035 | Decrease |
| Firmicutes | Ruminococcaceae | Uncultured | –5.59 | 0.014 | Decrease |
| Firmicutes | Ruminococcaceae | Ruminococcaceae UCG-010 | –5.97 | 0.035 | Decrease |
| Firmicutes | Lachnospiraceae | Lachnospiraceae UCG-010 | –6.32 | 0.078 | Decrease |
| Firmicutes | Ruminococcaceae | Candidatus Soleaferrea | –6.76 | 0.020 | Decrease |
| Firmicutes | Lachnospiraceae | Lachnospiraceae UCG-004 | –6.91 | 0.099 | Decrease |
| Bacteroidetes | Rikenellaceae | dgA-11 gut group | –7.60 | 0.008 | Decrease |
1Data derived from 6 to 7 pigs per treatment and analyzed using the DESeq2 package of R. All pigs were started on their assigned dietary treatment starting at –10 DPI. Experimental treatments: OA, ETEC-inoculated pigs receiving 1.0% OPN-enriched algal protein; PC, ETEC-inoculated pigs receiving 1.0% wild-type algal protein. Abbreviations: ETEC, enterotoxigenic E. coli; Padj, P-value adjusted by the Benjamini–Hochberg method to control for false discovery rate.