Table 3.
H. pylori and H. pylori-CagA Sero-Prevalence by Race and Cohort, in a Subset of the H. pylori-Colorectal Cancer Consortium (NYUWHS, PLCO, SCCS, WHI, and MEC), 1985–2009
| Cohort | H. pylori + | H. pylori + CagA + | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Whitesa |
African Americans |
Whitesa |
African Americans |
|||||||||||||||||
| n | % | n | % | PRb | 95%CI | PRc | 95%CI | PRd | 95%CI | n | % | n | % | PRb | 95%CI | PRc | 95%CI | PRd | 95%CI | |
| Total | 1,081 | 33 | 845 | 71 | 2.17 | 2.05, 2.31 | 1.96 | 1.83, 2.09 | 1.96 | 1.84, 2.10 | 638 | 19 | 732 | 62 | 3.19 | 2.94, 3.47 | 2.83 | 2.59, 3.10 | 2.87 | 2.62, 3.14 |
| NYUWHS | 193 | 47 | 34 | 62 | 1.32 | 1.05, 1.66 | 1.41 | 1.12, 1.77 | 1.34 | 1.04, 1.73 | 125 | 30 | 28 | 51 | 1.68 | 1.25, 2.26 | 1.68 | 1.25, 2.26 | 1.70 | 1.25, 2.32 |
| PLCO | 373 | 34 | 63 | 64 | 1.89 | 1.60, 2.24 | 1.80 | 1.52, 2.13 | 1.85 | 1.55, 2.20 | 233 | 21 | 53 | 54 | 2.55 | 2.06, 3.16 | 2.39 | 1.93, 2.97 | 2.46 | 1.97, 3.07 |
| SCCS | 85 | 49 | 454 | 77 | 1.56 | 1.33, 1.82 | 1.52 | 1.30, 1.78 | 1.51 | 1.29, 1.77 | 41 | 24 | 402 | 68 | 2.86 | 2.18, 3.75 | 2.75 | 2.09, 3.62 | 2.76 | 2.10, 3.63 |
| WHI | 361 | 26 | 89 | 55 | 2.12 | 1.80, 2.50 | 2.10 | 1.78, 2.47 | 2.03 | 1.71, 2.41 | 196 | 14 | 71 | 44 | 3.11 | 2.51, 3.87 | 3.17 | 2.53, 3.96 | 3.16 | 2.51, 3.98 |
| MEC | 69 | 31 | 205 | 73 | 2.40 | 1.95, 2.96 | 2.27 | 1.83, 2.81 | 2.28 | 1.84, 2.82 | 43 | 19 | 178 | 64 | 3.34 | 2.52, 4.44 | 3.23 | 2.43, 4.31 | 3.23 | 2.43, 4.30 |
Abbreviations: +, sero-positive; CagA, Cytotoxin-associated gene A; CI, confidence interval; MEC, Multiethnic cohort study; n, number; NYUWHS, New York University Women’s Health Study; PLCO, Prostate, Lung, Colorectal, and Ovarian Cancer Screening Study; PR, prevalence ratio; SCCS, Southern Community Cohort Study; WHI, Women’s Health Initiative.
Includes non-Latino and Latino whites.
Log-binomial regression models without further adjustment.
Log-binomial regression models with adjustment for age (continuous), sex, education (≤HS, technical school or some college, ≥college), and case-control status.
Log-binomial regression models with adjustment for age (continuous), sex, education (≤HS, technical school or some college, ≥college), case-control status, BMI (non-obese/obese), and smoking status (ever/never).