Table 2.
FullFitness (FF) scores and buried surface areas of the highest-scoring pose for 5b and 5c molecules docked to tubulin. FF scores were obtained from SwissDock, while the buried surface area was calculated using PyMOL.
Compound | FF score (kcal/mol) | Buried surface area (Å2) |
---|---|---|
5b | 4224.9 | 814 |
5c | 4298.7 | 859 |