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FullFitness (FF) scores and buried surface areas of the highest-scoring pose for 5b and 5c molecules docked to tubulin. FF scores were obtained from SwissDock, while the buried surface area was calculated using PyMOL.
| Compound | FF score (kcal/mol) | Buried surface area (Å2) |
|---|---|---|
| 5b | 4224.9 | 814 |
| 5c | 4298.7 | 859 |
