Fig 23. Patient pathology dynamics in secondary tauopathy.

(Left) Phase plane $(\tilde{u},\tilde{v})$ with three equilibria. (Right) When three different states co-exist, only the fully toxic state is stable as shown by the time-dynamics plot. (Parameters: a₀ = b₀ = a₁ = a₂ = b₁ = b₂ = 1, ${\tilde{a}}_1=3/4$, ${\tilde{b}}_1=4/3$, b₃ = 3). Note that trajectories are initialized by taking the initial condition ϵ = 0.005 away from an equilibrium point.