Table 2. Summary of efficacy and safety meta – analytic outcomes for EUS – guided LAMS and DPPS treatment of WON.
| LAMS – EUS | DPPS – EUS | P value 1 | |||||
| N studies | N patients | % (95 % CI) | N studies | N patients | % (95 % CI) | ||
| Safety Outcomes | |||||||
| Bleeding | 14 | 741 | 2.5 % (0.7 %, 5.5 %) |
10 | 381 | 4.6 % (1.2 %, 10.0 %) |
0.39 |
| Perforation | 12 | 545 | 0.5 % (0.0 %, 1.3 %) |
6 | 287 | 1.1 % (0.2 %, 2.6 %) |
0.35 |
| Stent migration | 15 | 788 | 5.9 % (2.6 %, 10.6 %) |
5 | 318 | 6.8 % (2.6 %, 12.8 %) |
0.79 |
| Stent occlusion | 13 | 730 | 3.8 % (0.9 %, 8.7 %) |
4 | 239 | 5.2 % (0.0 %, 19.0 %) |
0.78 |
| Efficacy Outcomes | |||||||
| Resolution of WON | 16 | 827 | 87.4 % (83.0 %, 91.3 %) |
15 | 614 | 87.5 % (80.1 %, 93.4 %) |
0.99 |
| Number of procedures to achieve resolution | 2 | 115 | 2.09 (1.05, 3.13) |
6 | 191 | 1.88 (1.48, 2.29) |
0.72 |
| Total unique studies or patients | 17 | 899 | 16 | 625 | |||
CI, confidence interval; LAMS, lumen-apposing metal stents; DPPS, double-pigtail plastic stents; WON, walled-off necrosis; EUS, endoscopic ultrasound.
1
P value for comparison of DPPS to LAMS