Fig. 1.

Skin microbiome evolution in healthy subjects as years go by. The graph provides a global overview of the relative abundance of major bacterial phyla of the human skin microbiota at different stages of life, measured by either 16S RNA or metagenomic approaches (DNA). Average data or main trends extracted from: newborns until 4 weeks (Dominguez-Bello et al. [8]), infants up to 12 months (Chu et al. [10] and Capone et al. [12]), children up to 10 years (Zhu et al. [15]), adolescents (Oh et al. [16]), adults (Ying et al. [17] and Grice et al. [4]), and older subjects above 60 years (Shibagaki et al. [23]). Csr cesarean delivery, Vgl vaginal delivery