Fig. 3.

The road to approval: from MARINE and ANCHOR to REDUCE-IT and US FDA and Health Canada approval. Along the way, there have been several key presentations and publications from REDUCE-IT, as well as numerous guideline endorsements. ACC American College of Cardiology, AHA American Heart Association, OM3FA omega-3 fatty acid, ADA American Diabetes Association, EAS European Atherosclerosis Society, ESC European Society of Cardiology, NLA National Lipid Association, EMDAC Endocrinologic and Metabolic Drugs Advisory Committee, FDA Food and Drug Administration