Table 1.

Summary of in vivo (adoptive transfer colitis) and ex vivo (gap closure) experiments.

Recipients	In vivo					Ex vivo
	DAI	Gross pathology	Intestinal inflammation	Intestinal fibrosis	Fibroblast activation	Fibroblast migration
Rag−/−	++++	++++	++++	++++	++++	++++
Rag−/−Dr3−/−	++**	++**	++*	+**	+**	++*
Rag−/−Dr3∆Col1a2	++++#	++++#	++++#	++*	++*	++*

+ Indicates activity of parameter measured, ranging from +: mild activity, to ++++: severe activity. DAI disease activity index. *Indicates p < 0.05, **p < 0.01 vs Rag^−/− ; ^#indicates p < 0.05 vs Rag^−/−Dr3^−/−.