Table 4.
(A) Univariable Analysis: Relationship between various clinical factors, urinary mRNA markers with the albumin excretion rates over 4 years among those with normoalbuminuria at baseline (n = 75). (B) Multivariable Analysis: Relationship between baseline level of podocyte detachment that is adjusted for various clinical factors with the albumin excretion rates over 4 years among those with normoalbuminuria at baseline (n = 75).
| Variable | Coefficient | SE | P value | 95% CI (LCL, UCL) |
|---|---|---|---|---|
| (A) | ||||
| Age (years) | 0.05 | 0.44 | 0.91 | − 0.82, 0.92 |
| Males | 6.31 | 8.40 | 0.45 | − 10.16, 22.78 |
| HbA1c (%) | − 8.30 | 4.94 | 0.09 | − 17.99, 1.38 |
| MAP (mm Hg) | 0.23 | 0.33 | 0.48 | − 0.42, 0.88 |
| eGFR (ml/min/1.73 m2) | − 0.16 | 0.26 | 0.54 | − 0.67, 0.35 |
| BMI (kg/m2) | 2.09 | 1.01 | 0.04 | 0.11, 4.07 |
| ARB or ACEi use | 1.97 | 8.48 | 0.82 | − 14.566, 18.60 |
| UPPod:CR (M/gCre) | 0.33 | 0.12 | 0.007 | 0.09, 0.57 |
| UPPod:Neph | − 0.38 | 0.35 | 0.28 | − 1.08, 0.31 |
| UPPod: Aqp2 | 1.86 | 4.63 | 0.69 | − 7.22, 10.95 |
| (B) | ||||
| UPPod:CR (M/gCre) | 0.47 | 0.14 | 0.001 | 0.20, 0.73 |
| Age (years) | − 0.27 | 0.52 | 0.98 | − 0.93, 0.90 |
| Males | 14.41 | 8.77 | 0.1 | − 2.77, 31.61 |
| BMI (kg/m2) | 3.10 | 1.06 | 0.003 | 1.02, 5.19 |
| MAP (mm Hg) | 0.11 | 0.34 | 0.74 | − 0.56, 0.78 |
| HbA1c (%) | − 7.14 | 4.92 | 0.15 | − 16.79,2.51 |
| eGFR (ml/min/1.73 m2) | − 0.35 | 0.30 | 0.24 | − 0.93, 0.23 |
| ARB or ACEI use | − 4.19 | 8.75 | 0.63 | − 21.34, 12.94 |