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. 2020 Oct 23;3:603. doi: 10.1038/s42003-020-01343-z

Fig. 4. PRL-2 is essential for arterial–venous patterning.

Fig. 4

a Retina whole-mount staining with isolectin B4 to quantify number of arteries and veins in P6 Ptp4a2fl/fl and Ptp4a2fl/fliEKO mice. b Retina whole-mount staining with isolectin B4 and a-SMA to quantify number of arteries and veins in P6 Ptp4a2+/+ and Ptp4a2−/− mice, and quantification of main vein and artery in c, d Ptp4a2fl/fl and Ptp4a2 fl/fliEKO mice, or e, f Ptp4a2+/+ and Ptp4a2−/− mice. g Retina whole-mount staining with isolectin B4 to see arteries in P21 Ptp4a2+/+ and Ptp4a2−/− mice, (h) and quantification (Mann–Whitney U test: **p value < 0.01, ****p value < 0.0001, ns nonsignificant p value > 0.05). Each individual data point represents a mouse. Scale bars: a, b 250 and 125 μm, g 500 μm. Error bars represent mean ± s.e.m.