Skip to main content
. 2020 Jul 25;26:95–110. doi: 10.1016/j.jare.2020.07.008

Fig. 4.

Fig. 4

Compound 7f could cause cycle arrest and induces apoptosis in the mitochondrial pathway in A549 or PC-9 cells. (A) a. Effect of compound 7f on cell cycle checkpoint associated proteins expression in A549 or PC-9 cells. b. Effects of compound 7f on MDM2 protein expression in A549 or PC-9 cells. (B) Effect of compound 7f on the apoptotic protein expression in A549 or PC-9 cells. (C) Compound 7f could enhance mitochondrial release of Cyto C and induce apoptosis (where *p < 0.05, **p < 0.01 and ***p < 0.005 compared to control).