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Results of biochemical tests and mice survival days’ analysis of compound 7f and PTX.
| Items | Control | PTX | 7f | Normal Range |
|---|---|---|---|---|
| ALT(U/L) | 65.53 ± 25.3 | 49.11 ± 17.2 | 62.14 ± 9.5 | 33.70 ~ 98.70 |
| AST(U/L) | 139.65 ± 24.20 | 151.16 ± 21.10 | 103.10 ± 18.60 | 69.70 ~ 322.90 |
| Glu (mmol/L) | 5.19 ± 1.27 | 6.99 ± 0.98 | 7.01 ± 1.02 | 2.65 ~ 7.62 |
| CRE(μmol/L) | 22.47 ± 2.36 | 17.02 ± 5.36 | 15.35 ± 2.10 | 19.43 ~ 64.97 |
| Median survival (Days) | 15.5 | 39 | 45.5 | – |
| P value | – | 0.0037** | ||
