Table 2.

Gene set enrichment analysis of target genes based on GO categories (1) cellular component, (2) molecular function and (3) biological processes

Cellular component	Total annotated genes in this class	No of genes	Percentage of genes	Fold value	p value (Bonferroni method)
Plasma membrane	3479	13	27.08333333	1.133555377	1
Cytosol	1178	13	27.08333333	3.347722423	0.062047052
Nucleoplasm	449	8	16.66666667	5.407513651	0.077139073
Cytoplasm	5684	32	66.66666667	1.707072486	0.07662906
Nucleus	5847	29	60.41666667	1.503955596	1
Extracellular	1825	15	31.25	2.493082014	0.420115356
Condensed nuclear chromosome	3	1	2.083333333	101.7128913	1
Chromosome passenger complex	3	1	2.083333333	101.7128913	1
Dynein complex	2	1	2.083333333	152.3163199	1
Molecular functions
Cytokine activity	107	3	6.25	10.61912371	0.638960909
Methyltransferase activity	59	3	6.25	19.25694677	0.114380528
Lipid kinase activity	35	3	6.25	32.45793855	0.024077901
Protein serine/threonine kinase activity	301	5	10.41666667	6.283525053	0.261224937
Metallopeptidase activity	101	4	8.333333333	14.9874087	0.032794018
Transcription factor activity	842	3	6.25	1.349571179	1
Oxidoreductase activity	161	1	2.083333333	2.368181983	1
Deacetylase activity	14	1	2.083333333	27.21634411	1
Receptor signalling protein tyrosine phosphatase activity	16	1	2.083333333	23.81642605	1
Biological processes
Protein metabolism	1323	7	14.58333333	2.000218678	1
Immune response	576	3	6.25	1.972690983	1
Regulation of cell cycle	57	2	4.166666667	13.30967968	1
Signal transduction	3934	18	37.5	1.728227217	1
Cell communication	3713	17	35.41666667	1.729421214	1
Nucleobase metabolism	2828	15	31.25	2.003652205	0.887230111
Apoptosis	220	1	2.083333333	1.73301188	1
Cell growth	1125	1	2.083333333	0.338912493	1
Cell cycle	22	1	2.083333333	17.32303243	1